|
KMID : 0948320070070010023
|
|
Konyang Medical Journal
2007 Volume.7 No. 1 p.23 ~ p.28
|
|
|
Comparison of Residual Curarization in Different Intermediate Acting Muscle Relaxants and Surgical Groups
|
|
Yang Chun-Woo
|
|
|
Abstract
|
|
|
Background: Postoperative residual curarization (PORC) increases postoperative pulmonary complications and
patient’s discomfort. Despite introducing of intermediate acting muscle relaxant (IAMR), PORC still show high incidence.
The aim of this study is to reveal the incidence of PORC with different IAMRs and surgical groups.
Methods: 214 ASA I or II, surgical patients receiving general anesthesia were classified into two groups according to IAMR: rocuronium (R), vecuronium (V) and three groups according to type of surgery: laparotomy (L), scopic surgery
(S) and nonlaparotomy (N). TOF values were measured three times at recovery room and calculated mean TOF. Mean TOF and incidences of PORC (TOF ratio < 0.7, < 0.9) were compared according to relaxant groups and surgical groups. Multiple regression test was carried for analyzing correlation between mean TOF and multiple factors.
Results: The incidences of PORC were 24.8% (TOF ratio < 0.7) and 50.0% (TOF ratio < 0.9) in all patients and
were not different between V and R group. The incidences of PORC (TOF ratio < 0.7, < 0.9) were lower in N group
(13%, 40%) than in L (32%, 53%) and S (36%, 63%) group. The time from last administration of relaxant to patient arrival at recovery room (Last dose-RR) was longest in N Group. Mean TOF was affected by Last dose-RR, body temperature and total dose of relaxant in order.
Conclusion: There are still high incidences of PORC with IAMRs.
|
|
|
KEYWORD
|
|
|
IAMR, PORC, TOF Values
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|